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global optimum

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anglais
As a result, finding a global optimum of a norm-based objective function is often tractable.
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There is no guarantee that the global optimum is found using this algorithm.
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In practice, the simplex algorithm is quite efficient and can be guaranteed to find the global optimum if certain precautions against "cycling" are taken.
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In particular, in global optimization, these methods can not certify that the output is really the global optimum.
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The method also models a method of coordinating economic-decisions so that decentralized firms behave so as to produce a global optimum.
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There are methods that can find the global optimum of these problems.
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If the function to be maximized is quasi-concave, or if the function to be minimized is quasi-convex, then a local optimum is also the global optimum.
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Although this technique is computationally expensive, its guarantee of a global optimum solution is useful in cases where only a few sequences need to be aligned accurately.
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Further, the injected randomness may enable the method to escape a local optimum and eventually to approach a global optimum.
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With ligands having up to 15-20 degrees of freedom (freely rotatable bonds) and complex nature of energy surface, global optimum search represents generally unsolved scientific task.
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