sulfonamide dans le dictionnaire Oxford-Hachette

anglais d'Amérique

Exemples monolingues (non-vérifiés par l'équipe de rédaction)

anglais
It is a fluorocarbon derivative, or perfluorinated compound, with eight carbons and a terminal sulfonamide functional group.
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The sulfonamide group was chosen to lower lipophilicity and increase solubility as seen in figure 7.
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The original antibacterial sulfonamides (sometimes called sulfa drugs or sulpha drugs) are synthetic antimicrobial agents that contain the sulfonamide group.
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The mechanism involves the deprotonation of the acyl sulfonamide followed by a 1,2-proton migration to give the alkoxide (3).
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Any sulfonamide can be considered as derived from a sulfonic acid by replacing a hydroxyl group with an amine group.
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The sulfonamide group forms a unique polar interaction with the enzyme.
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In patients who do not respond to sulfonamide treatment, other drugs, such as ampicillin, erythromycin, or minocycline, may be added.
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A primary amine will form a soluble sulfonamide salt which precipitates after addition of diluted hydrochloric acid.
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If the nucleophile is an alcohol the product is a sulfonate ester, if it is an amine the product is a sulfonamide.
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The newest statin, rosuvastatin has a unique polar methane sulfonamide group, which is quite hydrophilic and confers low lipophilicity.
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